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Case Study: Pernicious Anemia essay assignment
Ms. Rand is a 65-year-old woman who spends most of her day sitting on her porch and recovering from a recent surgery involving the removal of suspected cancerous lymph glands in the inguinal area. She is now complaining that her shoes are fitting too tightly, and she has developed poorly healing sores on her legs and ankles. A closer examination also shows distention in her varicose veins. Blood tests reveal a low level of proteins in the plasma.
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Case Study: Pernicious Anemia
Case Study: Pernicious Anemia
Question 1
Based on the patient history and the signs and symptoms, identify the fluid imbalance the patient is experiencing, and state the rationale for your answer.
Answers may vary.
Question 2
Discuss the four general causes of edema and how they apply in the case of this patient.
Answers may vary.
Question 3
Discuss the swelling, sores, varicose vein distention, and other effects that edema can have on a patient.
Case Study
Mr. Alvis, age 57, presented to his physician with marked fatigue, nausea with occasional diarrhea, and a sore, swollen tongue. Lately he also has been experiencing a tingling feeling in his toes and a feeling of clumsiness. Microscopic examination of a blood sample indicated a reduced number of erythrocytes, many of which are megaloblasts, and a reduced number of leukocytes, including many large, hypersegmented cells. Hemoglobin and serum levels of vitamin B12 were below normal. Additional tests confirm pernicious anemia.
Question 1
Relate the pathophysiology of pernicious anemia to the manifestations listed above.
Answers may vary.
Question 2
Discuss how the gastric abnormalities contribute to vitamin B12 and iron deficiency and how vitamin B12 deficiency causes complications associated with pernicious anemia.
Answers may vary.
Question 3
Discuss other tests that could be performed to diagnose this type of anemia.
Answers may vary.
Case Study: Pernicious Anemia
Question 4
Discuss the treatment available and the limitations.